Physical inactivity and arterial stiffness in COPD

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Physical inactivity and arterial stiffness in COPD

BACKGROUND Arterial stiffness is an important predictor of cardiovascular risk besides classic cardiovascular risk factors. Previous studies showed that arterial stiffness is increased in patients with COPD compared to healthy controls and exercise training may reduce arterial stiffness. Since physical inactivity is frequently observed in patients with COPD and exercise training may improve art...

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Determinants of arterial stiffness in COPD

BACKGROUND Cardiovascular morbidity and mortality is high in patients with chronic obstructive pulmonary disease (COPD) and arterial stiffness is a potentially modifiable risk factor with added predictive value beyond that obtained from traditional risk factors. Arterial stiffness has been the target of pharmacologic and exercise interventions in patients with COPD, but the effects appear limit...

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Physical inactivity in COPD and increased patient perception of dyspnea

OBJECTIVE To study patients' levels of exercise activity and the clinical characteristics that relate to physical activity and inactivity among patients with chronic obstructive pulmonary disease (COPD). METHODS A postal questionnaire was administered to 719 patients with COPD in 2010; patients were recruited from the Helsinki and Turku University Central Hospitals in Finland and have been fo...

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Quadriceps wasting and physical inactivity in patients with COPD.

Quadriceps weakness is an important complication of advanced chronic obstructive pulmonary disease (COPD) but few data exist concerning muscle bulk in early disease. We hypothesised that quadriceps bulk, measured by ultrasound rectus femoris cross-sectional area (USRF(CSA)), would be reduced in mild, as well as advanced, COPD compared with controls, and would correlate with physical activity. 1...

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The role of pulmonary arterial stiffness in COPD

COPD is the second most common cause of pulmonary hypertension, and is a common complication of severe COPD with significant implications for both quality of life and mortality. However, the use of a rigid diagnostic threshold of a mean pulmonary arterial pressure (mPAP) of ≥25 mHg when considering the impact of the pulmonary vasculature on symptoms and disease is misleading. Even minimal exert...

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ژورنال

عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease

سال: 2015

ISSN: 1178-2005

DOI: 10.2147/copd.s90943